About Duchenne Muscular Dystrophy
Duchenne Muscular Dystrophy is a progressive, muscle-wasting disorder that affects every muscle in the body. DMD is a recessive genetic mutation that occurs on the X chromosome. As a result, it almost exclusively affects boys. Unfortunately for the boys who have been diagnosed with DMD, it is the most severe of all the muscular dystrophies:
- Boys with this disease are diagnosed early, usually between 3 and 5 years of age.
- They lose muscle function quickly; many boys are in wheelchairs by age 10-12.
- They die early, most boys with DMD do not live to their mid-20’s.
Boys with DMD are unable to produce a functional dystrophin protein. Because they lack this protein, they first lose their skeletal muscle function, and then they lose their smooth muscle function (smooth muscles include the heart and diaphram).
Duchenne is currently 100% fatal. There is no cure and no truly effective treatment. Occasionally, a young man with DMD may live into his early thirties, but he will be in a wheelchair, he will need assistance breathing and he will live with the constant risk of heart failure.
There is no cure for Duchenne, but there is HOPE. Research is promising, but funds are needed to get drugs into trial and time is not on our side. Our mission on Everest to End to Duchenne is to not only raise money that will go directly to medical research, but to raise awareness of the severity of this disease. We will trek to Everest for these boys who cannot.